Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

• The Truth About Chronic Illness: How to Reset Your Nervous System & Slow Aging

  We’ve all had patients struggling with chronic conditions like long COVID, fibromyalgia, Lyme disease, and chronic fatigue. Despite all the tools in our functional medicine toolkit, there’s still something missing. How can we truly help them? I’m excited to have Ashok Gupta back on the New Frontiers podcast to offer a new take on healing from chronic illness. He explains that many chronic diseases stem from a malfunction in the brain's threat detection system, where the body overreacts to perceived threats, triggering immune, nervous system, or mood responses, creating a vicious cycle. Ashok shares how retraining the brain and calming the nervous system can reset the body’s response to chronic stress and presents the growing body of research supporting the Gupta Program, including new subjective measurements like CRP showing its impact. What excites me most is the potential for this approach to help some of my toughest-to-treat patients. With more studies emerging, I’m increasingly hopeful this could be a game-changer. It’s a conversation you won’t want to miss! ~DrKF Check out the show notes at https://tinyurl.com/2t55s3y3 for the full list of links and resources. GUEST DETAILS Ashok Gupta Email: [email protected] https://guptaprogram.com/ Ashok Gupta is an internationally recognized speaker, filmmaker, and health practitioner who specializes in supporting individuals with chronic illness. After overcoming ME (Chronic Fatigue Syndrome) through his own neuroplasticity research, Ashok developed the Gupta Program in 2007 to help others recover. He has published several medical papers and continues to research chronic conditions, with recent studies demonstrating the effectiveness of the Gupta Program. Ashok is dedicated to advancing holistic approaches to healing and improving outcomes for those facing chronic illness. THANKS TO OUR SPONSORS DIAMOND DUTCH: https://dutchtest.com/for-providers Biotics Research: https://www.bioticsresearch.com/ GOLD TimeLine Nutrition: https://tinyurl.com/bdzx2xms Vibrant Wellness: https://www.vibrant-wellness.com/ EXCLUSIVE OFFERS FROM OUR SPONSORS OneSkin: Get 15% off OneSkin with the code DRKARA at oneskin.co/DRKARA MiToQ: Target mitochondria for better health and longevity with MitoQ’s advanced supplements at mitoq.com/drkara CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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  1:06:19
• Hidden Mitochondria Problems Are Accelerating Your Age & Draining Your Health

  What if the key to reversing chronic disease, slowing cognitive decline, and boosting energy lies in the tiny powerhouses inside your cells—and we’ve finally found a way to protect them? We know mitochondria power our cells, but did you know they also create oxidative stress as they generate energy? Protecting mitochondrial health is critical—but most antioxidants can't reach inside the mitochondria where protection is needed most—until now. MitoQ, a scientifically advanced, mitochondria-targeted antioxidant developed by visionary researchers in New Zealand penetrates mitochondria up to 90%, offering protection where it's needed most. In this episode with Dr. Siobhan Mitchell, we dive into how MitoQ is transforming the way we tackle chronic disease, inflammation, and cognitive decline. From improving heart health to supporting brain function, MitoQ is changing the game. It’s something I’m using personally and recommending to most of my patients. Listen in to discover how this powerful tool can help you support your patients at the cellular level—before symptoms even appear. ~DrKF Check out the show notes at https://tinyurl.com/2t55s3y3 for the full list of links and resources. GUEST DETAILS Dr Siobhan Mitchell, PhD., MitoQ Chief Scientific Officer Email: [email protected] Holding a PhD in neuroscience from SUNY Albany, Siobhan Mitchell has also completed a post-doctoral fellowship on brain aging at the University of Washington. She has over 15 years of clinical research experience, seven patents on mood and cognitive food products, and has authored over 50 papers on aging, brain health, nutrition, metabolic health and more. With a personal passion for brain aging research, Siobhan has worked on metabolic and skin health, appetite, sports physiology and of cellular health –which she now focuses on as the Chief Scientific Officer for research-backed cellular health company, MitoQ – creators of the world’s first mitochondria-targeted antioxidant. THANKS TO OUR SPONSOR MitoQ: https://www.mitoQ.com/partner [email protected] OFFER FOR NEW FRONTIERS LISTENERS Practitioners - Sign up to become a MitoQ Partner, access wholesale rates, and Unlock Cellular Health for your Patients by going to https://www.mitoq.com/partner CONNECT WITH DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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  1:12:21
• p-Tau 217: The Breakthrough Biomarker Revolutionizing Early Alzheimer’s Detection

  Join me for a fascinating conversation around an exciting breakthrough in dementia detection that’s offering real hope for early intervention. Dr. Hans Frykman, Chief Scientific Officer at Neurocode Laboratories, is here to share groundbreaking insights into cutting-edge biomarkers that can identify pathology associated with Alzheimer's disease before symptoms even appear. What’s even more fascinating is how these same tools are revealing neuroinflammation caused by infections, including COVID, Lyme disease, and mold exposure—issues that are incredibly relevant in functional medicine today. The assays Dr. Frykman and his team have developed, and continue to research, are transforming the way we think about diagnosing and addressing neurodegeneration. We’re talking about a potential game-changer that allows us to intervene earlier, reverse damage, and ultimately improve the trajectory of these conditions. This is an extraordinary time in science and medicine, and the work we’re discussing today is at the forefront of it all. Don’t miss out on how this could reshape your practice. ~DrKF Check out the show notes at https://tinyurl.com/2t55s3y3 for the full list of links and resources. GUEST DETAILS Dr. Hans Frykman, MD PhD FRCPC [email protected] Hans Frykman MD, Ph.D., FRCPC is the founder, CEO, and medical director of BC Neuroimmunology Lab located in the UBC hospital on the University of BC campus in Vancouver BC. He is the medical director for Lykke Lab a genetics laboratory also on the University of BC campus. Also, he is the CSO for Neurocode Lab Inc. in Bellingham WA, a high-complexity, specialty lab focused on neuroimmunology and biomarkers in neurodegeneration. Dr. Frykman has a clinical faculty position at the University of British Columbia, Faculty of Medicine, Division of Neurology. THANK YOU TO OUR SPONSORS DIAMOND DUTCH: https://dutchtest.com/for-providers Biotics Research: https://www.bioticsresearch.com/ GOLD TimeLine Nutrition: https://tinyurl.com/bdzx2xms Vibrant Wellness: https://www.vibrant-wellness.com/ EXCLUSIVE OFFERS FROM OUR SPONSORS OneSkin: Get 15% off OneSkin with the code DRKARA at oneskin.co/DRKARA Try Qualia NAD+ for up to 50% off! Visit http://qualialife.com/kara15 and use code KARA15 at checkout for an additional 15% off your entire purchase! Why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. https://tinyurl.com/2b5benmd Want more? CONNECT WITH DrKF Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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  1:07:49
• Cutting-Edge Metabolomic Testing for IBS, Longevity, and Metabolic Health

  We’re witnessing an exciting shift in how we understand gut health and disease—and it’s all thanks to the powerful metabolites produced by the microbiome, like short-chain fatty acids (SCFAs) and secondary bile acids. In today’s episode, Dr. Tom Fabian shares groundbreaking insights into how these postbiotics influence intestinal barrier integrity, immune balance, and even muscle regeneration. These compounds are also connected to key processes like glucose metabolism and healthy aging. What’s truly fascinating is how this science is opening up new frontiers in treating IBS, metabolic conditions, and chronic gut issues. With the upcoming launch of Diagnostic Solution Laboratories’ StoolOMX test, an add-on to the GI-MAP, we now have a tool to measure these metabolites in clinical practice, making personalized and effective treatments more attainable. This is a pivotal moment in functional medicine that you don’t want to miss. ~DrKF FOLLOW ALONG WITH THE CONVERSATION! Get the Updated GI-MAP® Guide with StoolOMX™ Insights! The new GI-MAP® Guide now includes StoolOMX™ insights on bile acids and short-chain fatty acids, enhancing your understanding of IBS, IBD, and gut motility. Refine treatment strategies and optimize patient care with this essential resource. Download now! https://tinyurl.com/5ehysjp7 Check out the show notes at https://tinyurl.com/2t55s3y3 for the full list of links and resources. GUEST DETAILS Thomas Fabian, PhD, CNTP Email: [email protected] Dr. Fabian is a leading expert on the role of the microbiome in health, immune function, chronic disease, and aging. As a translational scientist, his primary focus is on the clinical application of microbiome research in the integrative and functional medicine space. He received his PhD in molecular biology from the University of Colorado, Boulder, and has worked as a biomedical researcher in the biotechnology industry, and more recently, as a consultant in the microbiome testing field. Currently, Dr. Fabian serves a consultant and science advisor with Diagnostic Solutions Laboratory, and he is also a Science Advisory Board member with Designs for Health. In addition, he is certified as a Nutrition Therapy Practitioner by the Nutrition Therapy Institute in Denver. THANKS TO OUR SPONSOR Diagnostic Solutions Laboratory: https://www.diagnosticsolutionslab.com/ Phone: 877-485-5336 CONNECT WITH DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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  1:01:56
• A Fresh Take on Exposomics: Resiliency Factors That Offset Environmental Risks

  It’s very difficult (often impossible) to completely avoid many of the environmental toxins that can cause harm - like air pollution and forever chemicals that contaminate our water and food supply. But Drs. Bob and Rosalind Wright at Mount Sinai have a hopeful solution to this dilemma. They are pioneering the study of “resiliency factors,” not just “risk factors,” that can offset the risks of harmful exposures. It’s a fresh and welcome take on exposomics that I am very excited to share with you. For instance - did you know that omega-3 intake during pregnancy can protect against the development of asthma in the child, even if the child is exposed to known risk factors for asthma? Or that positive relationships (ones that create a sensitive, positive, caregiving environment) have been shown to potentially mitigate the effects of environmental toxins? As a practitioner, I am always looking to empower patients with real solutions to the health challenges we inevitably face and I hope you enjoy this conversation as much as I did. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Dr. Rosalind J. Wright, MD, MPH and Robert O. Wright, MD, MPH Icahn School of Medicine at Mount Sinai https://icahn.mssm.edu/ Dr. O. Robert Wright is the Ethel H. Wise Chair of Environmental Medicine at Mount Sinai and co-founder of the Institute for Exposomic Research. His research links environmental exposures, like those tracked in the PROGRESS cohort, with the developmental origins of diseases. Dr. Rosalind J. Wright is Dean for Public Health at Icahn School of Medicine and Co-Director of the Institute for Climate Change, Environmental Health, and Exposomics. A pioneer in environmental health, she studies how early-life exposures influence chronic diseases and has been NIH-funded for over 23 years. She also mentors the next generation of clinical scientists. THANKS TO OUR SPONSORS DIAMOND DUTCH: https://tinyurl.com/4anbz7b3 Biotics Research: https://www.bioticsresearch.com/ Integrative Therapeutics: https://tinyurl.com/4emwj48z GOLD OneSkin: http://oneskin.co/DRKARA TimeLine Nutrition: https://tinyurl.com/bdzx2xms Vibrant Wellness: https://www.vibrant-wellness.com/ EXCLUSIVE OFFERS FROM OUR SPONSORS Try QUALIA NAD+ for up to 50% off! Visit https://www.qualialife.com/kara15 and use code KARA15 at checkout for an additional 15% off your entire purchase. OneSkin: Get 15% off OneSkin with the code DRKARA at oneskin.co/DRKARA CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Group Program: https://tinyurl.com/4hvusavw Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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  1:09:32

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